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( a ) Hierarchical <t>heatmap</t> depicting the relative abundance of each protein across the three different types of EVs, with darker shades of red indicating higher relative abundance (measured by NSAF) (protein names shown represent 1 out of every 22 proteins for clarity). ( b ) Zoomed-in view on the region of the heatmap with a higher abundance in cell surface proteins in SC5314 YEVs. Proteins described as immunogenic in the Candida Genome Database (CGD) are marked with an asterisk.
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Effects of JX granules on differentially expressed proteins in HF rats. The volcano plots ( A ) and <t>Heatmaps</t> ( B ) of differentially expressed proteins.Their expression is calculated by log2 method and displayed in the volcano plots and heatmaps in different colors, where red represents significantly up-regulated proteins, blue represents significantly down-regulated proteins, and gray part represents no quantitative information of proteins. DEPs differentially expressed proteins, M model group, J JX granules, Z control group
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( a ) Hierarchical heatmap depicting the relative abundance of each protein across the three different types of EVs, with darker shades of red indicating higher relative abundance (measured by NSAF) (protein names shown represent 1 out of every 22 proteins for clarity). ( b ) Zoomed-in view on the region of the heatmap with a higher abundance in cell surface proteins in SC5314 YEVs. Proteins described as immunogenic in the Candida Genome Database (CGD) are marked with an asterisk.

Journal: International Journal of Molecular Sciences

Article Title: From High Protection to Lethal Effect: Diverse Outcomes of Immunization Against Invasive Candidiasis with Different Candida albicans Extracellular Vesicles

doi: 10.3390/ijms26010244

Figure Lengend Snippet: ( a ) Hierarchical heatmap depicting the relative abundance of each protein across the three different types of EVs, with darker shades of red indicating higher relative abundance (measured by NSAF) (protein names shown represent 1 out of every 22 proteins for clarity). ( b ) Zoomed-in view on the region of the heatmap with a higher abundance in cell surface proteins in SC5314 YEVs. Proteins described as immunogenic in the Candida Genome Database (CGD) are marked with an asterisk.

Article Snippet: The NSAF values, which are calculated considering the number of matched peptide spectra (PSMs) and the molecular weight, were used to conduct a clustering heatmap analysis with Rstudio ( a).

Techniques:

Effects of JX granules on differentially expressed proteins in HF rats. The volcano plots ( A ) and Heatmaps ( B ) of differentially expressed proteins.Their expression is calculated by log2 method and displayed in the volcano plots and heatmaps in different colors, where red represents significantly up-regulated proteins, blue represents significantly down-regulated proteins, and gray part represents no quantitative information of proteins. DEPs differentially expressed proteins, M model group, J JX granules, Z control group

Journal: Chinese Medicine

Article Title: Mechanism of jianxin granules in the treatment of heart failure based on proteomics and metabolomics

doi: 10.1186/s13020-024-01009-6

Figure Lengend Snippet: Effects of JX granules on differentially expressed proteins in HF rats. The volcano plots ( A ) and Heatmaps ( B ) of differentially expressed proteins.Their expression is calculated by log2 method and displayed in the volcano plots and heatmaps in different colors, where red represents significantly up-regulated proteins, blue represents significantly down-regulated proteins, and gray part represents no quantitative information of proteins. DEPs differentially expressed proteins, M model group, J JX granules, Z control group

Article Snippet: Multivariate analyses, including 2D Hierarchical Cluster Analysis (HCA) Heatmaps and Principal Component Analysis (PCA) plots, were performed using Qlucore Omics Explorer (Qlucore, Lund Sweden).

Techniques: Expressing, Control